Pharmaceutical Delivery Systems
For a long time, disorders of the inner ear could not be treated because of its inaccessibility and fear of damaging connected organs (such as the vestibular organ).
Substances applied to the outer ear do not easily pass through the tympanic membrane, the round window membrane to the middle and inner ear and resorption of the linings of the inner ear is not well documented.
However, drugs using Phospholipids in liposomal formulations have already been successfully delivered into the inner ear. Other ointments used for treating ear infections could also make use of the delivery form to accelerate the speed of diffusion through the eardrum.